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Welcome to the Department of Urology, Institute of Medical Science (IMSUT) Hospital, The University of Tokyo

The University of Tokyo was the first national university in Japan and has contributed the development of modern medical science. IMSUT Hospital Urology was established in July, 2020 by the urologists of the University of Tokyo.

We provide a comprehensive environment for the diagnosis and treatment of urologic cancer, dysuria, overactive bladder, and urinary incontinence. We offer laparoscopic surgery and robotic surgery by board-certified surgeons, which are recognized as minimally invasive care for adrenal tumors, renal cancer, ureteral cancer and prostate cancer. In addition to surgery, we use the latest knowledge to propose drug treatment, chemotherapy, and radiotherapy. Evidence-based medicine is our principle.

科長:高橋さゆり

We are also engaged in basic research to develop innovative drugs for castration resistant prostate cancer in the field of nuclear receptor signaling.

We are located in Shirokanedai, one of the most popular residential neighborhoods in central Tokyo with convenient access to transportation.

We welcome international patients. There is limousine bus access from Narita and Haneda International airports to the Sheraton Miyako Hotel Tokyo, which is conveniently located nearby our hospital.

Sayuri Takahashi M.D.,Ph.D.
Director
Department of Urology, IMSUT Hospital

Medical Tourism

We have served international patients suffered from urological cancer from China, Korea, France and USA. Sheraton Miyako hotel Tokyo is convenient for patients and the family to visit our hospital, which is located about 5 minutes on foot.

Letter from International Patient

Letter from International Patient

Our Team

Haruki Kume M.D.,Ph.D.

Haruki Kume M.D.,Ph.D.
Professor (IMSUT Hospital & Tokyo University Hospital)

Sayuri Takahashi M.D.,Ph.D.
Director
Department of Urology, IMSUT Hospital
Project Associate professor

Sayuri Takahashi M.D.,Ph.D.

Sayuri Takahashi M.D.,Ph.D. is a the deputy director of Urology at IMSUT Hospital and a project senior assistant professor. Dr. Takahashi is board certified in Urology by the Japanese Urological Association and in endocrinology by the Japan Endocrine Society, Japanese Board of Cancer Therapy. She is a board-certified surgeon of laparoscopic surgery and robotic surgery by the Japan Society of Endoscopic Surgery and Japanese Society of Endourology.

Dr.Takahashi has an expertise in laparoscopic surgery and robotic surgery in the treatment of prostate cancer, kidney cancer, and bladder tumor.

Dr. Takahashi completed a residency in Urology at the Tokyo University Hospital and Mitsui Memorial Hospital. She engaged in robotic surgery as a senior assistant professor at the Tokyo University Hospital since 2014. She completed an observership of the art minimally invasive surgical techniques, such as robotic radical nerve sparing prostatectomy, robotic partial nephrectomy, robotic cystectomy by professor Inderbir Gill at the University of Southern California on 2016 with the financial support by the 2016 AUA/JUA Academic Scholar program.

Dr.Takahashi engaged in basic research on prostate cancer and earned her Doctorate of Medicine from the University of Tokyo. She completed her post-doctoral training at the Brady Urological Institute at Johns Hopkins Medicine.

Dr. Takahashi is a member of the American Urologic Society and European Association of Urology. She earned the 101th JUA annual meeting award on 2013, 8th Young Research Grant by JUA on 2014, the Award by Japanese Foundation for Prostate Research on 2014, EAU Best Poster Award on 2015, “Women‘s Challenge Grand Prize” from Gender equality Bureau Cabinet Office of Japanese Government on 2024, and The University of Tokyo GAP fund program on 2024.

Jun Takahashi M.D.
Project assistant professor (IMSUT Hospital)

Fusako Niimi M.D.
(IMSUT Hospital)

Aki Kikuchi M.D.
(IMSUT Hospital)

Kisumi Yomoda M.D.
(IMSUT Hospital)

Thoshiya Sasaki M.D.
(IMSUT Hospital)

Daisuke Yamada M.D.,Ph.D.
Director of Tokyo Metropolitan Police Hospital

Yuta Yamada M.D.,Ph.D.
Senior Assistant Professor (Tokyo University Hospital)

Akira Nomiya M.D.
Kantorosai Hospital

Satoru Taguchi M.D.,Ph.D.
Senior Assistant Professor (Tokyo University Hospital)

Jun Kamei M.D.,Ph.D.
Senior Assistant Professor (Tokyo University Hospital)

Sachi Yamamoto M.D.
Kantorosai Hospital

Yoichi Fujii M.D.,Ph.D.
Assistant Professor (Tokyo University Hospital)

Daiji Watanabe M.D., Ph.D.
Assistant Professor (Tokyo University Hospital)

Ichiro Takada Ph.D.

Treatment & Services

For local residents of Minato-ku, Tokyo, the Minato-ku city hall offers a ticket which can be used for a prostate cancer screening.

We recommend that all men over 50-years-old take a blood sampling screening for prostate cancer.

Our areas of expertise are;

Adrenal tumor
Urologic oncology-
  • Kidney tumor (Renal tumor)
  • Renal pelvic cancer
  • Urethral cancer
  • Bladder tumor
  • Prostate cancer
  • Testicular tumor
  • Overactive bladder
  • Incontinence
  • Renal Ureteral Stone
  • Prostate enlargement

IMSUT Hospital Urology offers minimally invasive treatments by qualified surgeons.

  • Robotic-assisted prostatectomy
  • Robotic-assisted partial nephrectomy
  • Laparoscopic adrenalectomy
  • Laparoscopic nephrectomy
  • Laparoscopic nephroureterectomy
  • Trans-urethral resection of bladder tumor
  • Trans-urethral resection of prostate
  • Trans-urethral lithotripsy, Flexible trans-urethral lithotripsy
  • BOTOX injection for overactive bladder
  • Other open surgery
  • Ultrasound-guided transperineal prostate biopsy

Exception:

  • Unfortunately, we are not specialists of sexual infection, ED, or dermatology.

Request Appointment

Central appointment office 03-5449-5560
International calling +81-3-5449-5560
Appointment office opening hours:
8:30 A.M. to 5:00 P.M., Monday through Friday

Clinic schedule and physician appointment availability times

Clinic schedule and physician appointment availability times

** Available in English.

Private Rooms

We have several private rooms with a bathroom on 5th floor.
The room charge is not covered by national health insurance.

Private room A

Private room A
38㎡

Private room B

Private room B
26㎡

Private room C

Private room C
10㎡

Basic Research

Our team is engaged in basic research of prostate cancer.

Takada I, Hidano S, Nakagawa T, Nakagawa S, Makishima M, Takahashi S.*
The Role of ESS2/DGCR14: Is It an Essential Factor in Splicing and Transcription?
Int J Mol Sci. 2025 Apr 25;26(9):4056
Taguchi S, Kawai T, Ambe Y, Kishitani K, Noda M, Kaneko T, Miyakawa J, Nakamura Y, Hoshina H, Obinata D, Yamaguchi K, Kakutani S, Furuya Y, Sato Y, Adachi Y, Sugimoto K, Sato K, Tabata M, Tanaka T, Nara K, Uemura Y, Kamei J, Akiyama Y, Sato Y, Yamada Y, Niimi A, Yamada D, Takada T, Takahashi S, Yamada Y, Miyazaki H, Enomoto Y, Nishimatsu H, Fujimura T, Fukuhara H, Nakagawa T, Takahashi S, Kume H.
Physical, but not laboratory, treatment-related adverse events are associated with favorable outcomes of enfortumab vedotin for advanced urothelial carcinoma: A landmark analysis
Int J Urol. 2025 Mar;32(3):270-276.
Takahashi S
Editorial Comment to “Management of apalutamide‐induced rash with focus on early peaks”
Int J Urol. 2025 Jan;32(1):117.
Takahashi S
SPECIALTY SOCIETIES Promoting Diversity in the Japanese Urological Association
AUANews January 2025
Takahashi S*, Takada I, Hashimoto K, Yokoyama A, Nakagawa T, Makishima M, Kume H.
ESS2 controls prostate cancer progression through recruitment of chromodomain helicase DNA binding protein 1.
Sci Rep.2023;13(1):12355.
Takahashi S*, Takada I.
Recent advances in prostate cancer: WNT signaling, chromatin regulation and transcriptional coregulators
Asian J Androl.2023;25(2):158-165.
Takahashi S*.
Carrent Trend of CAR-T Cell Therapy for Metastatic Castration-Resistant Prostate Cancer
Jpn J Cancer Chemother.2023;50(10):1038-1042.
Iimura1 Y, Iihara H, Aoyama T, Ishibashi M, Sasuga C, Furukawa N, Anzai E, Ijichi Y, Takahashi S, Tabata M, Niimi F, Kaneko J, Izukuri K, Baba K, Boku N, Kuroda S.
Study Protocol for a Prospective Observational Study to Evaluate the Efficacy of Fosnetupitant for Long-Delayed Chemotherapy-Induced Nausea and Vomiting in Patients Receiving Platinum-Based Chemotherapy (LODEC-N)
J Clin Trials.2023;13 (4) No: 1000360.
Takada I‡, Hidano S‡, Takahashi S‡, Ogawa H, Tsuchiya M, Yokoyama A, Sato S, Ochi H, Nakagawa T, Kobayashi T, Nakagawa S, Makishima M.
‡Authors equally contributed
Transcriptional coregulator Ess2 controls survival of post-thymic CD4+ T cells through the Myc and IL-7 signaling pathways
Journal of Biological Chemistry. 2022;298(9):102342.
Hagiwara K, Sakamoto A, Sasaki K, Kanatani A, Kimura M, Kaneko T, Takahashi S, Yamada Y, Nakagawa T.
Higher serum alkaline phosphatase value indicates the need for bone mineral density testing in non-metastatic prostate cancer patients undergoing androgen deprivation therapy.
Jpn J Clin Oncol. 2022;52(1):73-80.
Takahashi S*.
Editorial Comment to Successful establishment of crowdfunding to develop new diagnostic tools for chronic prostatitis
Int J Urol. 2022; 29(6):602-603.
Naito A, Takeshima Y, Takahashi S.
Mammary-type myofibroblastoma of the perineum: typical or rare location?
IJU Case Rep. 2022; 23;5(3):161-164.
Yamada D, Kawai T, Sato Y, Yamada Y, Akiyama Y, Miyakawa J, Takahashi S, Kume H.
Trends in prostate cancer diagnosis during the COVID-19 crisis: A report from one high-volume Japanese center
GHM Open. 2021;1(1):28-30. Communication
Takahashi S*.
Editorial Comment to Treatment-induced changes in levels of brain natriuretic peptide in prostate cancer patients receiving gonadotropin-releasing hormone antagonists or agonists
Int J Urol. 2020;27(4):356.
Takada I, Tsuchiya M, Yanaka K, Hidano S, Takahashi S, Kobayashi T, Ogawa H, Nakagawa S, Makishima M
Ess2 bridges transcriptional regulators and spliceosomal complexes via distinct interactingdomains.
Biochem Biophys Res Commun. 2018; 4;497(2):597-604.
Takahashi S, Aruga S, Yamamoto Y, Matsumoto T, Kitamura T, Homma Y.
Urinary Oxalate Excretion Decreased in Androgen Receptor-Knockout Mice by Suppressing Oxalate Synthesis in The Liver.
Open Journal of Urology. 2015;5(8),123-132.
Takahashi S, Shiraishi T, Miles N, Trock BJ, Kulkarni P, Getzenberg RH.
Nanowire analysis of cancer-testis antigens as biomarkers of aggressive prostate cancer.
Urology. 2015;85(3):704.e1-7.
Terada N, Shiraishi T, Zeng Y, Aw-Yong KM, Mooney SM, Liu Z, Takahashi S, Luo J, Lupold SE, Kulkarni P, Getzenberg RH.
Correlation of sprouty1 and JAGGED1 with aggressive prostate cancer cells with different sensitivities to androgen deprivation.
J Cell Biochem. 2014; 115(9):1505-15.
Teshima T, Takahashi S*, Nagamoto S, Miyazaki H, Nakagawa T, Fujimura T, Fukuhara H, Kume H, and Homma Y.
Intrascrotal Dedifferentiated Leiomyosarcoma Originating from Dartos Muscle
Case Reports in Urology. 2014; Article ID 841929, 3 pages.
Tsumura K, Yoshida K, Yamamoto S, Takahashi S, Iida K, and Enomoto Y.
A Case of the Nutcracker Syndrome Developed after Delivery
Case Reports in Urology. 2014; Article ID 503017, 3 pages.
Matsumoto T, Sakari M, Okada M, Yokoyama A, Takahashi S, Kouzmenko A, Kato S.
The androgen receptor in health and disease
Annu Rev Physiol. 2013;75;201-24.
Takahashi S*, Hirano Y, Kawamura T, Homma Y.
Intraurethral condylomata acuminate associated with genital piercings.
Int J STD AIDS. 2013; 24(1):67-9.
Taguchi S, Takahashi S, Iida K, Mizutani T, Yamaguchi K, Tominaga T, Niwa N, Yoshimi M, Takahashi T, Homma Y.
Spermatic Cord Lymphoma: A Case Report and Literature Review
Case Reports in Medicine. 2012; Article ID513703, 4pages.
Takahashi S, Watanabe T, Okada M, Inoue K, Ueda T, Takada I, Watabe T, Yamamoto Y, Fukuda T, Nakamura T, Akimoto C, Fujimura T, Hoshino M, Imai Y, Metzger D, Miyazono K, Minami Y, ChambonP, Kitamura T, Matsumoto T, Kato S.
Noncanonical Wnt signaling mediates androgen-dependent tumor growth in a mouse model of prostate cancer.
Proc Natl Acad Sci USA. 2011; 108(12):4938-43.
Uemura K, Takahashi S, Shintani-Ishida K, Nakajima M, Saka K, Yoshida K
A Death Due to Perirenal Hematoma Complicating Extracorporeal Shockwave Lithotripsy
J Forensic Sci. 2008; (53) 469-47.
Ohtake F, Baba A, Takada I, Okada M, Iwasaki K, Miki H, Takahashi S, Kouzmenko A, Nohara K, Chiba T, Fuji-Kuriyama Y, Kato S.
Dioxin receptor is a ligand-dependent E3 ubiquitin ligase.
Nature. 2007; 446(7135); 562-566.
Shina H, Matsumoto T, Sato T, Igarashi K, Miyamoto J, Takemasa S, Sakari M, Takada I, Nakamura T, Metzger D, Chambon P, Kanno J, Yoshikawa H, Kato S.
Premature ovarian failure in androgen receptor-deficient mice.
Proc Natl Acad Sci USA. 2006; 103(1):224-229.
Kume H, Tomita K, Takahashi S, Fukutani K.
Irinotecan as a new agent for urachal cancer.
Urol Int. 2006;76(3):281-2.
Takahashi S, Kato S.
Androgen Receptor and Prostate Cancer Development.
Medical Science Digest. 2005, 31(3):12-15.
Kato S, Sato T, Watanabe T, Takemasa S, Masuhiro Y, Ohtake F, Matsumoto T.
Funtion of nuclear sex hormone receptors in gene regulation.
Cancer Chemother Pharmacol. 2005; (56) Suppl1:4-9 Review
Takahashi S, Minowada S, Tomita K, Katumata N, Tanaka T, Kitamura T.
Massive Aderenocortical Adenoma Following Long-Term Treatment of 21-Hydroxylase Deficiency
J Urol. 2002; 167;1390-1391.

News

April 25th, 2025

Assistant professor Takahashi made a presentation at AACR(American Associate for Cancer Research) annual meeting2025 in Chicago.

AACR

AACR

April 18th, 2025

Director Takahashi made a speech on EAU/JUA Business meeting in 112th JUA Annual meeting in Fukuoka.

112th JUA

April 17th,2025

Director Takahashi and Prof Lih-Ming Wong from University of Melbourne permed Violin & Piano Duo at International party on 112th JUA Annual meeting in Fukuoka.

<Program>

Csárdás by Monti Waltzing Mathilda Arranged by Stephan Koncz arranged by Kai Chen Lim.

112th JUA

112th JUA

112th JUA

April 10th,2025

Dr. Ignasio from the Republic of Chile visited our hospital and observed robotic surgeries.

February 27th, 2025

Director Takahashi facilitated a session of the robotic surgery as the chairperson at annual meeting of NORTH AMERICAN ROBOTIC UROLOGY Society(NARUS2025) in Las Vegas.

NARUS2025

December 17th, 2024

Director Takahashi hold the IMSUT Hospital Christmas concert at Tommy Holl. 150 patients and guests enjoyed her piano recital.

<Program>

J.Sibelius 5 pieces The fir Op75-5
⇒you tube https://www.youtube.com/watch?v=F6QUPVKazXI

W.A.Mozart Piano Sonata k330

Saint-Saëns=A.Siloti Carnival of the Animals: XIII. Le Cygne (The Swan)
⇒you tube https://www.youtube.com/watch?v=9kOzqobmUjk&list=RD9kOzqobmUjk&start_radio=1

Shumannn=Liszt Widmung

F.Chopin Nocturn No5 op15-2

F.Chopin Grande Valse No2 op34-1

(encore ) F.Chopin Heroic polonaise op53

IMSUT Hospital Christmas concert

IMSUT Hospital Christmas concert

June 26th, 2024

Director Takahashi wan the "Women's Challenge Grand Prize" by Gender equality Bureau Cabinet Office of Japanese government.

Women's Challenge Grand Prize

Our Location

IMSUT Hospital

4-6-1 Shiroganedai, Minato-ku, Tokyo, Japan
108-8639
Tel +81-3-3443-8111

Department of Urology, IMSUT Hospital The Institute of Medical Science, The University of Tokyo

Transportation

Subway Tokyo Metro Tokyo Metro
Nanboku Line Shirokanedai Station
Toei Subway Toei Subway
Mita Line Shirokanedai Station
Toei Bus
Toei Bus
Route: 黒77 (KURO-77) /
橋86 (HASHI-88)
Bus Stop: Tōdai-Ikaken-Byōin-Nishimon
(Inst.Of Medical Science.Univ.Of Tokyo Hp.)
Route: 品93 (SHINA-93)
Bus Stop: Shirokanedai Sta.
Car Hospital parking located
in front of the bldg. 1.

IMSUT Campus Map

IMSUT Campus Map

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